Journal CE · 1 CEC

Reactive Hyperemia: Revisiting a Key Vascular Feature of Cardiorespiratory Fitness

Cardiorespiratory fitness depends on more than the heart and lungs—it also relies on the ability of the vascular system to deliver oxygen efficiently to working muscles. This course explores the emerging role of reactive hyperemia as a comprehensive measure of vascular function that captures…

About this course

Exercise and Sport Sciences Reviews, Volume 54 • Number 3 • July 2026 | DOI: 10.1249/JES.0000000000000389

What you will learn

  • Compare the physiological information provided by reactive hyperemia and flow-mediated dilation as measures of vascular function and cardiorespiratory fitness
  • Examine the vascular and microvascular mechanisms that contribute to reactive hyperemia, including resistance vessel reactivity, endothelial signaling, and skeletal muscle perfusion
  • Evaluate the evidence supporting reactive hyperemia as a sensitive marker of exercise-induced vascular adaptations, endurance training status, and aerobic fitness

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